ABHD16B

Across TCGA patient cohorts, ABHD16B RNA expression is significantly associated with the go_rna of many other GO terms, with 621 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible ABHD16B-associated GO terms across cancer lineages are Establishment or maintenance of monopolar cell polarity, Early endosome to recycling endosome transport, and Reticulophagy. Each is linked with ABHD16B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD16B-to-partner and partner-to-ABHD16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of monopolar cell polarity grouped by ABHD16B-low versus ABHD16B-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD16B→partner) and Y-score (partner→ABHD16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Establishment or maintenance of monopolar cell polarity →	+0.156	+0.904	<.001	<.001	3	1
SCLC	Early endosome to recycling endosome transport →	+0.122	+0.784	<.001	<.001	3	1
SCLC	Reticulophagy →	+0.091	+0.569	<.001	.001	3	1
SCLC	Pyrimidine nucleobase metabolic process →	+0.120	+0.629	<.001	<.001	3	1
SCLC	Regulation of DNA repair →	+0.037	+0.641	<.001	<.001	3	1
SCLC	Transcription-coupled nucleotide-excision repair →	+0.118	+0.952	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 621 associations by consensus.

Establishment or maintenance of monopolar cell polarity by ABHD16B expression — SCLC

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