Across TCGA pan-cancer cohorts, ABHD16B RNA is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ABHD16B data layer compared with 6 for mutation status.
The strongest signal is observed in small cell lung cancer (SCLC), where higher ABHD16B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ABHD16B expression acts as an unfavorable survival marker, although some lineages such as SCLC show a favorable association.
SCLC are the cancer types where ABHD16B RNA most reproducibly stratifies survival.