ABHD16B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD16B mutation is significantly associated with the RNA expression of many other genes, with 468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD16B-associated genes across cancer lineages are PRDX4P1, RNASE12, and SLC20A1P3. Each is linked with ABHD16B in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD16B-to-partner and partner-to-ABHD16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX4P1 grouped by ABHD16B-low versus ABHD16B-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD16B→partner) and Y-score (partner→ABHD16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADPRDX4P1 →+0.213+3.396<.001.00733
BLCARNASE12 →+0.084+7.640<.001.00932
BLCASLC20A1P3 →+0.049+7.640<.001.00932
LUADRNU6-1318P →+0.706+4.319<.001.00732
LUADVN1R21P →+0.111+4.372.007.00732
STADACTR3BP5 →+0.146+3.663<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 468 associations by consensus.

PRDX4P1 by ABHD16B expression — STAD

Box plot of PRDX4P1 in ABHD16B-low vs ABHD16B-high samples in STAD.

Explore this box plot interactively →

Exploration