ABHD16B

Across TCGA patient cohorts, ABHD16B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD16B-associated genes across cancer lineages are Caspase-7-cleavedD198, 14-3-3_beta, and ERK2. Each is linked with ABHD16B in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD16B-to-partner and partner-to-ABHD16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ABHD16B-low versus ABHD16B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD16B→partner) and Y-score (partner→ABHD16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.772	+2.999	.002	.035	3	3
UCEC	14-3-3_beta →	-0.098	-1.687	.022	.044	3	1
UCEC	ERK2 →	+0.235	+3.321	.004	.009	3	1
UCEC	IGFBP2 →	-0.623	-1.700	.023	.044	3	1
UCEC	JNK2 →	+0.254	+2.331	.002	.019	3	1
UCEC	MEK1 →	+0.380	+2.321	.014	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Caspase-7-cleavedD198 by ABHD16B expression — UCEC

Explore this box plot interactively →