ABHD16B

Across TCGA cell cohorts, ABHD16B mutation is significantly associated with the RNA expression of many other genes, with 651 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD16B-associated genes across cancer lineages are PROP1, PRSS54, and SRRD. Each is linked with ABHD16B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD16B-to-partner and partner-to-ABHD16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROP1 grouped by ABHD16B-low versus ABHD16B-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD16B→partner) and Y-score (partner→ABHD16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PROP1 →	+0.013	+3.643	<.001	.002	3	2
BLOOD_Lymphoma	PRSS54 →	+0.043	+4.867	.001	.009	3	1
LARGE_INTESTINE	SRRD →	+0.751	+3.169	.001	.009	3	1
LARGE_INTESTINE	JOSD1 →	+0.521	+3.364	.007	.002	3	1
LARGE_INTESTINE	TNRC6B →	+0.829	+3.364	<.001	.002	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.750	+3.364	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 651 associations by consensus.

PROP1 by ABHD16B expression — OVARY

Explore this box plot interactively →