ABHD15

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD15 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ABHD15-associated genes across cancer lineages are CMP, Eosinophils, and pDC. Each is linked with ABHD15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD15-to-partner and partner-to-ABHD15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by ABHD15-low versus ABHD15-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD15→partner) and Y-score (partner→ABHD15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCCMP →+0.020+3.315.038.04031
LUSCEosinophils →+0.058+3.173<.001.04931
UCECpDC →+0.087+2.818.003.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CMP by ABHD15 expression — LUSC

Box plot of CMP in ABHD15-low vs ABHD15-high samples in LUSC.

Explore this box plot interactively →

Exploration