ABHD14A-ACY1

Across TCGA pan-cancer cohorts, ABHD14A-ACY1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ABHD14A-ACY1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ABHD14A-ACY1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ABHD14A-ACY1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, KIRC, and BRCA are the cancer types where ABHD14A-ACY1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.159	0.661	.001	33	view →
KIRC	OS	Median	All	0.125	0.881	<.001	12	view →
BRCA	OS	Median	All	0.308	0.924	<.001	12	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
COAD	DFS	Median	II,III,IV	0.140	0.756	.001	6	view →
UCEC	OS	Median	All	0.959	0.659	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ABHD14A-ACY1–HNSC (OS)

Open the HNSC breakdown →