ABHD13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD13 mutation is significantly associated with the RNA expression of many other genes, with 4,736 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD13-associated genes across cancer lineages are NUS1, ANKRD49P3, and PIMREGP4. Each is linked with ABHD13 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD13-to-partner and partner-to-ABHD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUS1 grouped by ABHD13-low versus ABHD13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD13→partner) and Y-score (partner→ABHD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNUS1 →+0.359+2.021.003.00133
CESCANKRD49P3 →+0.032+3.103<.001.00933
SKCMPIMREGP4 →+0.082+3.825.001.00233
UCECUBE2D3 →+0.318+2.137.001<.00133
UCECMETTL14 →+0.335+2.279.001<.00133
UCECATP6V1B2 →+0.409+3.321<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,736 associations by consensus.

NUS1 by ABHD13 expression — UCEC

Box plot of NUS1 in ABHD13-low vs ABHD13-high samples in UCEC.

Explore this box plot interactively →

Exploration