ABHD13

Across TCGA pan-cancer cohorts, ABHD13 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ABHD13’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ABHD13 RNA is repressed in tumor relative to normal tissue. In most cancer types ABHD13 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and HNSC are the cancer types where ABHD13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABHD13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.508	<.001	11	view →
THCA	Male	III,IV	−0.630	<.001	10	view →
HNSC	All	All	+0.376	.001	9	view →
LUSC	All	All	−0.400	<.001	7	view →
STAD	All	II,III,IV	+0.659	<.001	6	view →
LUAD	Female	II,III,IV	−0.604	<.001	6	view →
CHOL	Male	All	+1.136	.012	4	view →
KIRC	Male	III,IV	−0.355	.011	4	view →
COAD	Male	II,III,IV	+0.385	.011	3	view →
ESCA	All	All	+0.717	.004	2	view →
UCEC	All	All	−0.614	.002	2	view →
BRCA	All	All	−0.149	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ABHD13–KICH

Open the KICH breakdown →