ABHD13

Across TCGA patient cohorts, ABHD13 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD13-associated genes across cancer lineages are Caspase-7-cleavedD198, A-Raf_pS299, and Rictor_pT1135. Each is linked with ABHD13 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABHD13-to-partner and partner-to-ABHD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ABHD13-low versus ABHD13-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD13→partner) and Y-score (partner→ABHD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.325	+2.824	<.001	.034	3	3
UCEC	A-Raf_pS299 →	-0.140	-3.169	<.001	<.001	3	2
UCEC	Rictor_pT1135 →	-0.076	-1.847	.018	.007	3	2
UCEC	S6_pS240_S244 →	+0.282	+2.222	.027	.010	3	2
UCEC	STAT3_pY705 →	-0.341	-2.169	<.001	.002	3	2
UCEC	ATM →	-0.370	-2.209	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Caspase-7-cleavedD198 by ABHD13 expression — COAD

Explore this box plot interactively →