ABHD12

Across TCGA patient cohorts, ABHD12 mutation is significantly associated with the RNA expression of many other genes, with 976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD12-associated genes across cancer lineages are OR7E105P, CNN2P10, and TRMU. Each is linked with ABHD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD12-to-partner and partner-to-ABHD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E105P grouped by ABHD12-low versus ABHD12-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD12→partner) and Y-score (partner→ABHD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR7E105P →	+0.153	+3.020	<.001	.006	3	2
BLCA	CNN2P10 →	+0.027	+3.173	.003	.009	3	2
UCEC	TRMU →	+0.454	+3.491	<.001	.002	3	2
UCEC	CINP →	+0.284	+2.276	.007	.005	3	2
UCEC	CACTIN →	+0.412	+4.010	.001	<.001	3	2
UCEC	EXOSC8 →	+0.476	+2.928	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 976 associations by consensus.

OR7E105P by ABHD12 expression — BLCA

Explore this box plot interactively →