ABHD10

Across TCGA pan-cancer cohorts, ABHD10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ABHD10 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ABHD10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ABHD10 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

PDAC, COAD, and UCEC are the cancer types where ABHD10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.493	0.326	.003	39	view →
COAD	DFS	Median	All	1.000	0.888	.023	12	view →
UCEC	DFS	Median	All	0.936	1.000	.021	12	view →
CCRCC	OS	Median	All	0.949	0.832	.031	1	view →
HNSC	OS	Median	IV	0.741	0.926	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ABHD10–PDAC (DFS)

Open the PDAC breakdown →