ABHD1

Across TCGA cell cohorts, ABHD1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible ABHD1-associated genes across cancer lineages are NOBOX, NLRP2B, and RPH3A. Each is linked with ABHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD1-to-partner and partner-to-ABHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOBOX grouped by ABHD1-low versus ABHD1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD1→partner) and Y-score (partner→ABHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	NOBOX →	+0.013	+3.459	<.001	.002	3	1
URINARY_TRACT	NLRP2B →	+0.020	+3.050	.005	.007	3	1
URINARY_TRACT	RPH3A →	+0.053	+4.000	<.001	.002	3	1
LARGE_INTESTINE	PATE1 →	+0.006	+5.415	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

NOBOX by ABHD1 expression — URINARY_TRACT

Explore this box plot interactively →