ABHD1

Across TCGA pan-cancer cohorts, ABHD1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ABHD1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ABHD1 RNA is repressed in tumor relative to normal tissue. In most cancer types ABHD1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where ABHD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABHD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	IV	−0.765	<.001	10	view →
COAD	All	III,IV	+0.250	<.001	10	view →
THCA	Male	III,IV	−0.592	<.001	9	view →
BRCA	Female	All	−0.365	<.001	6	view →
KIRC	Male	All	+0.245	<.001	6	view →
BLCA	All	All	+0.317	.004	5	view →
CHOL	All	All	−0.617	<.001	4	view →
LUSC	All	All	+0.318	<.001	4	view →
HNSC	All	All	−0.252	.003	4	view →
READ	All	All	+0.276	.007	3	view →
LUAD	All	All	+0.200	.001	3	view →
PRAD	All	All	+0.263	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ABHD1–KICH

Open the KICH breakdown →