ABCG4

Across TCGA patient cohorts, ABCG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,097 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCG4-associated proteins across cancer lineages are FLNA_S2128, SULF1, and THY1. Each is linked with ABCG4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCG4-to-partner and partner-to-ABCG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCG4 versus FLNA_S2128 in CCRCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCG4→partner) and Y-score (partner→ABCG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FLNA_S2128 →	+0.898	+0.084	.003	<.001	3	4
LUAD	SULF1 →	+0.759	+0.056	<.001	<.001	3	4
GBM	THY1 →	+0.743	+0.624	<.001	<.001	3	4
BRCA	MAP4K5 →	+0.235	+0.076	.001	.001	3	3
GBM	ARHGAP30_S709 →	-0.546	-0.310	.001	.007	3	3
LSCC	NDRG4 →	+0.893	+0.239	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,097 associations by consensus.

ABCG4 vs FLNA_S2128 — CCRCC

Explore this scatter interactively →