ABCG4

Across TCGA cell cohorts, ABCG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,216 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCG4-associated GO terms across cancer lineages are Lipoprotein localization, Lipoprotein transport, and Nucleoside triphosphate metabolic process. Each is linked with ABCG4 in more than 14 cancer types. Because this analysis shows association rather than direction, both ABCG4-to-partner and partner-to-ABCG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein localization grouped by ABCG4-low versus ABCG4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCG4→partner) and Y-score (partner→ABCG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Lipoprotein localization →	+0.107	+0.199	.001	.006	3	15
LUNG_SCLC	Lipoprotein transport →	+0.117	+0.642	.002	.001	2	13
LUNG_SCLC	Nucleoside triphosphate metabolic process →	+0.083	+0.868	.001	<.001	3	11
BREAST	Cell division →	+0.092	+0.275	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.085	+0.135	<.001	.007	3	10
LARGE_INTESTINE	Regulation of protein localization to centrosome →	+0.083	+0.196	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,216 associations by consensus.

Lipoprotein localization by ABCG4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →