ABCG1

Across TCGA pan-cancer cohorts, ABCG1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABCG1 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher ABCG1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ABCG1 expression acts as an unfavorable survival marker.

THYM, LUAD, and ESCA are the cancer types where ABCG1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LUAD	OS	Median	II,III,IV	0.053	0.751	<.001	36	view →
ESCA	DFS	Median	II,III,IV	0.159	0.525	.008	30	view →
LIHC	OS	Median	II,III,IV	0.239	0.715	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABCG1–THYM (OS)

Open the THYM breakdown →