ABCD4

Across TCGA pan-cancer cohorts, ABCD4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ABCD4 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ABCD4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ABCD4 expression acts as an unfavorable survival marker.

LUAD, GBM, and UCEC are the cancer types where ABCD4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.663	1.000	.007	13	view →
GBM	DFS	Median	All	0.235	0.516	.001	10	view →
UCEC	DFS	Quartile	III,IV	0.421	1.000	.040	8	view →
HNSC	DFS	Median	All	0.532	1.000	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ABCD4–LUAD (OS)

Open the LUAD breakdown →