ABCD3

Across TCGA patient cohorts, ABCD3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,435 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ABCD3-associated genes across cancer lineages are ZEB2, MEOX2, and CXCL12. Each is linked with ABCD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCD3-to-partner and partner-to-ABCD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCD3 versus ZEB2 in COAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCD3→partner) and Y-score (partner→ABCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZEB2 →	-0.554	-0.272	.001	<.001	3	6
HNSC	MEOX2 →	-0.937	-0.418	<.001	.001	3	5
COAD	CXCL12 →	-1.285	-0.354	<.001	<.001	3	5
UCEC	CNRIP1 →	-0.716	-0.535	.001	.003	3	5
BRCA	ETS1 →	-0.550	-0.716	.003	<.001	3	5
GBM	CYP1B1 →	-0.946	-0.258	.007	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,435 associations by consensus.

ABCD3 vs ZEB2 — COAD

Explore this scatter interactively →