ABCD1

Across TCGA cell cohorts, ABCD1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,401 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ABCD1-associated genes across cancer lineages are ATP6AP1, RAB43, and FAM3A. Each is linked with ABCD1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ABCD1-to-partner and partner-to-ABCD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCD1 versus ATP6AP1 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCD1→partner) and Y-score (partner→ABCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ATP6AP1 →	+1.072	+1.455	<.001	.001	2	14
SOFT_TISSUE	RAB43 →	+1.319	+1.022	<.001	<.001	3	13
BONE	FAM3A →	+1.257	+1.468	<.001	<.001	3	12
LUNG_NSCLC_LUSC	IKBKG →	+1.193	+1.697	.004	<.001	2	13
BONE	SLC10A3 →	+1.265	+0.985	.005	.001	2	12
LARGE_INTESTINE	ARMC5 →	+0.799	+1.467	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,401 associations by consensus.

ABCD1 vs ATP6AP1 — UPPER_AERODIGESTIVE_TRACT

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