ABCD1

Across TCGA cell cohorts, ABCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,747 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ABCD1-associated GO terms across cancer lineages are Very long-chain fatty acid catabolic process, Fatty-acyl-CoA transport, and Thioester transport. Each is linked with ABCD1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ABCD1-to-partner and partner-to-ABCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Very long-chain fatty acid catabolic process grouped by ABCD1-low versus ABCD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCD1→partner) and Y-score (partner→ABCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Very long-chain fatty acid catabolic process →	+0.221	+1.895	<.001	<.001	3	19
LUNG_SCLC	Fatty-acyl-CoA transport →	+0.654	+1.372	<.001	<.001	3	18
LUNG_SCLC	Thioester transport →	+0.654	+1.372	<.001	<.001	3	18
BREAST	Positive regulation of lipid catabolic process →	+0.121	+1.239	.002	.008	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.076	+1.184	<.001	.003	3	13
LUNG_SCLC	Fatty acid transmembrane transport →	+0.174	+1.549	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,747 associations by consensus.

Very long-chain fatty acid catabolic process by ABCD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →