ABCC9

Across TCGA cell cohorts, ABCC9 mutation is significantly associated with the RNA expression of many other genes, with 436 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCC9-associated genes across cancer lineages are OR11H2, OR2A12, and HEPHL1. Each is linked with ABCC9 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC9-to-partner and partner-to-ABCC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H2 grouped by ABCC9-low versus ABCC9-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC9→partner) and Y-score (partner→ABCC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR11H2 →	+0.038	+4.865	.007	<.001	3	3
BLOOD_Myeloma	OR2A12 →	+0.006	+4.807	<.001	.006	3	2
LUNG_SCLC	HEPHL1 →	+0.113	+3.386	<.001	.008	3	2
BLOOD_Leukemia	TLX1 →	+1.150	+3.744	.001	.003	3	2
BLOOD_Leukemia	RGR →	+0.020	+4.099	<.001	<.001	3	2
BLOOD_Leukemia	CCKAR →	+0.022	+3.239	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 436 associations by consensus.

OR11H2 by ABCC9 expression — OVARY

Explore this box plot interactively →