ABCC13

Across TCGA patient cohorts, ABCC13 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCC13-associated genes across cancer lineages are FoxM1, INPP4B, and JNK_pT183_Y185. Each is linked with ABCC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCC13-to-partner and partner-to-ABCC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ABCC13-low versus ABCC13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC13→partner) and Y-score (partner→ABCC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.243	+2.000	.037	.032	3	1
UCEC	INPP4B →	-0.297	-3.169	.041	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.200	-1.986	.008	.032	3	1
UCEC	Ku80 →	+0.309	+2.013	.003	.018	3	1
UCEC	MEK1 →	+0.488	+3.807	.003	<.001	3	1
UCEC	mTOR_pS2448 →	-0.153	-3.302	.023	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

FoxM1 by ABCC13 expression — UCEC

Explore this box plot interactively →