ABCC11

Across TCGA cell cohorts, ABCC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,886 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ABCC11-associated GO terms across cancer lineages are ER-nucleus signaling pathway, Golgi vesicle transport, and Vacuolar transport. Each is linked with ABCC11 in more than 8 cancer types. Because this analysis shows association rather than direction, both ABCC11-to-partner and partner-to-ABCC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ER-nucleus signaling pathway grouped by ABCC11-low versus ABCC11-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC11→partner) and Y-score (partner→ABCC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ER-nucleus signaling pathway →	+0.098	+0.116	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.078	+0.113	<.001	.001	3	8
KIDNEY	Vacuolar transport →	+0.056	+0.127	.001	.002	3	8
URINARY_TRACT	Lysosomal transport →	+0.054	+0.153	.003	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.117	+0.137	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.087	+0.085	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,886 associations by consensus.

ER-nucleus signaling pathway by ABCC11 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →