ABCC11

Across TCGA pan-cancer cohorts, ABCC11 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ABCC11 data layer compared with 7 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ABCC11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ABCC11 expression acts as an unfavorable survival marker, although some lineages such as THCA and UCS show a favorable association.

THCA, UCS, and KIRP are the cancer types where ABCC11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	II,III,IV	1.000	0.303	<.001	68	view →
UCS	DFS	Median	II,III,IV	0.574	0.149	.001	48	view →
KIRP	DFS	Median	IV	0.039	0.623	.001	37	view →
LUAD	OS	Median	All	0.759	0.861	<.001	31	view →
SKCM	DFS	Quartile	All	0.257	0.154	.006	23	view →
ACC	DFS	Quartile	II,III,IV	0.407	0.929	.004	20	view →
CHOL	DFS	Quartile	II,III,IV	0.146	0.816	.002	20	view →
BLCA	OS	Quartile	All	0.703	0.380	<.001	18	view →
DLBC	DFS	Median	III,IV	0.525	1.000	.013	15	view →
READ	OS	Quartile	All	1.000	0.459	.025	10	view →
STAD	OS	Quartile	IV	0.668	0.122	.016	6	view →
CESC	DFS	Median	All	0.686	0.786	.047	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ABCC11–THCA (DFS)

Open the THCA breakdown →