ABCC11

Across TCGA cell cohorts, ABCC11 mutation is significantly associated with the RNA expression of many other genes, with 120 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCC11-associated genes across cancer lineages are OR56A4, SMYD1, and PRAMEF9. Each is linked with ABCC11 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCC11-to-partner and partner-to-ABCC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A4 grouped by ABCC11-low versus ABCC11-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC11→partner) and Y-score (partner→ABCC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR56A4 →	+0.016	+5.977	<.001	.001	3	2
STOMACH	SMYD1 →	+0.033	+3.280	<.001	.004	3	2
PANCREAS	PRAMEF9 →	+0.005	+4.614	<.001	.004	3	2
OVARY	DPRX →	+0.094	+3.754	<.001	.002	3	2
LUNG_NSCLC_LUAD	RGSL1 →	+0.053	+2.830	<.001	.005	3	2
LUNG_NSCLC_LUAD	ACP4 →	+0.059	+3.091	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

OR56A4 by ABCC11 expression — SOFT_TISSUE

Explore this box plot interactively →