Across TCGA patient cohorts, ABCB8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,530 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABCB8-associated proteins across cancer lineages are CDK5, RHEB, and COPG2. Each is linked with ABCB8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCB8-to-partner and partner-to-ABCB8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB8→partner) and Y-score (partner→ABCB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDK5 →	+0.384	+0.396	<.001	<.001	3	7
OV	RHEB →	+0.408	+0.511	<.001	.001	3	6
BRCA	COPG2 →	+0.319	+0.570	<.001	<.001	3	5
LUAD	TNPO3 →	+0.300	+0.385	<.001	.004	3	5
LUAD	ARF5 →	+0.258	+0.513	<.001	<.001	3	4
GBM	PDAP1 →	+0.367	+0.513	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,530 associations by consensus.

Exploration

ABCB8 survival (RNA) · tumor vs normal (RNA) · all ABCB8 data types