Across TCGA patient cohorts, ABCB8 mutation is significantly associated with the RNA expression of many other genes, with 4,263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCB8-associated genes across cancer lineages are NF1P10, UBFD1P1, and MED15P6. Each is linked with ABCB8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCB8-to-partner and partner-to-ABCB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB8→partner) and Y-score (partner→ABCB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NF1P10 →	+0.241	+4.569	<.001	.005	3	4
LUAD	UBFD1P1 →	+0.061	+4.197	<.001	.009	3	3
LUAD	MED15P6 →	+0.180	+4.279	.002	.001	3	3
UCEC	ATP5PF →	+0.404	+1.828	.001	<.001	3	3
UCEC	SLBP →	+0.561	+2.332	<.001	<.001	3	3
UCEC	NDUFS4 →	+0.495	+2.332	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,263 associations by consensus.

Exploration

ABCB8 survival (RNA) · tumor vs normal (RNA) · all ABCB8 data types