Across TCGA cell cohorts, ABCB8 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCB8-associated genes across cancer lineages are TEX33, CLEC1B, and CCDC60. Each is linked with ABCB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCB8-to-partner and partner-to-ABCB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB8→partner) and Y-score (partner→ABCB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TEX33 →	+0.027	+5.266	<.001	.001	3	2
LUNG_SCLC	CLEC1B →	+0.045	+5.029	<.001	.006	3	1
OVARY	CCDC60 →	+0.064	+4.228	<.001	.006	3	1
OVARY	C1orf146 →	+0.040	+4.450	<.001	.004	3	1
LUNG_NSCLC_LUAD	OPN1LW →	+0.057	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR51D1 →	+0.052	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

ABCB8 survival (RNA) · tumor vs normal (RNA) · all ABCB8 data types