ABCB4

Across TCGA patient cohorts, ABCB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,741 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABCB4-associated proteins across cancer lineages are HNMT, LRP1, and VWF. Each is linked with ABCB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCB4-to-partner and partner-to-ABCB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB4 versus HNMT in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB4→partner) and Y-score (partner→ABCB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HNMT →	+0.484	+0.620	<.001	<.001	3	6
BRCA	LRP1 →	+0.540	+0.336	<.001	<.001	3	6
BRCA	VWF →	+0.469	+0.330	<.001	<.001	3	5
UCEC	WIPF1 →	+0.264	+0.393	<.001	.003	3	5
UCEC	CHAF1A_S141 →	-0.659	-0.469	<.001	.002	3	5
PDAC	CNN3 →	+0.682	+0.607	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,741 associations by consensus.

ABCB4 vs HNMT — UCEC

Explore this scatter interactively →