ABCB11

Across TCGA patient cohorts, ABCB11 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,051 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ABCB11-associated GO terms across cancer lineages are Response to insulin, Stress-activated protein kinase signaling cascade, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with ABCB11 in more than 19 cancer types. Because this analysis shows association rather than direction, both ABCB11-to-partner and partner-to-ABCB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to insulin grouped by ABCB11-low versus ABCB11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB11→partner) and Y-score (partner→ABCB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to insulin →	+0.055	+0.146	<.001	<.001	3	20
STAD	Stress-activated protein kinase signaling cascade →	+0.054	+0.139	<.001	<.001	3	19
STAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.061	+0.138	<.001	<.001	3	19
STAD	Actin filament depolymerization →	+0.054	+0.194	<.001	<.001	3	18
STAD	Regulation of intracellular protein transport →	+0.055	+0.133	<.001	<.001	3	18
STAD	Golgi vesicle budding →	+0.064	+0.129	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,051 associations by consensus.

Response to insulin by ABCB11 expression — STAD

Explore this box plot interactively →