ABCB11

Across TCGA patient cohorts, ABCB11 protein abundance is significantly associated with the RNA expression of many other genes, with 1,734 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCB11-associated genes across cancer lineages are ACSS3, AGBL2, and TRBV14. Each is linked with ABCB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCB11-to-partner and partner-to-ABCB11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB11 versus ACSS3 in GBM, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB11→partner) and Y-score (partner→ABCB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACSS3 →	+0.970	+1.000	.009	.006	3	2
HNSC	AGBL2 →	-1.072	-0.544	.001	.005	3	2
OV	TRBV14 →	+1.327	+0.714	.004	.003	3	2
UCEC	SLC25A27 →	-1.169	-0.556	.009	.007	3	2
UCEC	TPTE2P5 →	-1.079	-0.390	.005	.002	3	2
UCEC	TUBA8 →	-0.632	-0.392	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,734 associations by consensus.

ABCB11 vs ACSS3 — GBM

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