ABCB11

Across TCGA cell cohorts, ABCB11 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,007 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCB11-associated GO terms across cancer lineages are Cell-substrate junction assembly, Cell-substrate junction organization, and Mammary gland development. Each is linked with ABCB11 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCB11-to-partner and partner-to-ABCB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by ABCB11-low versus ABCB11-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB11→partner) and Y-score (partner→ABCB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cell-substrate junction assembly →	+0.175	+0.596	<.001	<.001	3	6
PANCREAS	Cell-substrate junction organization →	+0.157	+0.514	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Mammary gland development →	+0.110	+0.257	<.001	.008	3	6
SKIN	Regulation of erythrocyte differentiation →	+0.052	+0.031	<.001	.007	3	5
STOMACH	Regulation of ventricular cardiac muscle cell action potential →	+0.160	+0.116	<.001	.003	3	5
PANCREAS	Regulation of protein localization to cell periphery →	+0.048	+0.411	.009	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,007 associations by consensus.

Cell-substrate junction assembly by ABCB11 expression — PANCREAS

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