ABCA9

Across TCGA patient cohorts, ABCA9 mutation is significantly associated with the RNA expression of many other genes, with 5,796 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCA9-associated genes across cancer lineages are SNHG25, PARP2, and EME1. Each is linked with ABCA9 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA9-to-partner and partner-to-ABCA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNHG25 grouped by ABCA9-low versus ABCA9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA9→partner) and Y-score (partner→ABCA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNHG25 →	+0.471	+2.019	.006	.001	3	4
UCEC	PARP2 →	+0.530	+2.550	<.001	<.001	3	4
UCEC	EME1 →	+0.618	+1.936	<.001	<.001	3	4
COAD	CHAC2 →	+0.847	+3.926	<.001	<.001	3	4
UCEC	FBXO22 →	+0.451	+1.617	<.001	<.001	3	4
UCEC	MRPS11 →	+0.371	+1.514	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,796 associations by consensus.

SNHG25 by ABCA9 expression — SKCM

Explore this box plot interactively →