ABCA9

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ABCA9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,020 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ABCA9-associated GO terms across cancer lineages are Golgi vesicle transport, Chemical synaptic transmission, postsynaptic, and Viral process. Each is linked with ABCA9 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCA9-to-partner and partner-to-ABCA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by ABCA9-low versus ABCA9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA9→partner) and Y-score (partner→ABCA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTGolgi vesicle transport →+0.053+0.112.001.00937
LARGE_INTESTINEChemical synaptic transmission, postsynaptic →-0.067-0.067<.001.00836
UPPER_AERODIGESTIVE_TRACTViral process →+0.096+0.143<.001.00235
BONEResponse to amino acid starvation →+0.046+0.467.006.00717
BONECellular response to amino acid starvation →+0.049+0.471.003.00626
UPPER_AERODIGESTIVE_TRACTLate viral transcription →+0.113+0.118<.001.00435
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,020 associations by consensus.

Golgi vesicle transport by ABCA9 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Golgi vesicle transport in ABCA9-low vs ABCA9-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration