ABCA9

Across TCGA cell cohorts, ABCA9 mutation is significantly associated with the RNA expression of many other genes, with 872 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCA9-associated genes across cancer lineages are CCNP, PIGL, and MYH3. Each is linked with ABCA9 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCA9-to-partner and partner-to-ABCA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNP grouped by ABCA9-low versus ABCA9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA9→partner) and Y-score (partner→ABCA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCNP →	+0.978	+2.043	.005	.008	3	2
LARGE_INTESTINE	PIGL →	+0.648	+3.321	.003	.003	3	2
LARGE_INTESTINE	MYH3 →	+0.495	+2.043	.007	.008	3	2
LARGE_INTESTINE	TTC19 →	+0.656	+3.169	<.001	.006	3	2
LARGE_INTESTINE	COMMD2 →	+0.436	+2.043	.009	.008	3	2
LARGE_INTESTINE	CTBS →	+0.701	+2.743	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 872 associations by consensus.

CCNP by ABCA9 expression — LARGE_INTESTINE

Explore this box plot interactively →