Across TCGA patient cohorts, ABCA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,954 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ABCA4-associated proteins across cancer lineages are GCLM, ARHGAP29, and EIF3J. Each is linked with ABCA4 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCA4-to-partner and partner-to-ABCA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA4→partner) and Y-score (partner→ABCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GCLM →	+0.746	+1.428	<.001	<.001	3	5
UCEC	ARHGAP29 →	+0.475	+0.787	.002	<.001	3	5
OV	EIF3J →	-0.284	-0.947	.001	.002	3	3
GBM	ARHGAP18 →	+0.442	+0.242	<.001	<.001	3	3
LUAD	ARHGAP29_S21 →	+0.525	+1.434	.002	.001	3	3
LSCC	ATP7A →	+0.310	+1.706	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,954 associations by consensus.

Exploration

ABCA4 survival (RNA) · tumor vs normal (RNA) · all ABCA4 data types