Across TCGA patient cohorts, ABCA4 protein abundance is significantly associated with the RNA expression of many other genes, with 223 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABCA4-associated genes across cancer lineages are CEP128, SEL1L2, and PRPS2. Each is linked with ABCA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCA4-to-partner and partner-to-ABCA4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA4→partner) and Y-score (partner→ABCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CEP128 →	+0.627	+1.145	.005	.002	3	1
BRCA	SEL1L2 →	-0.063	-1.004	.003	.003	3	1
BRCA	PRPS2 →	+0.882	+0.970	.004	.003	3	1
BRCA	PARP4 →	+1.357	+1.137	<.001	<.001	3	1
BRCA	CYB5B →	+0.701	+1.076	.005	.001	3	1
BRCA	NECAB2 →	-0.698	-1.244	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 223 associations by consensus.

Exploration

ABCA4 survival (RNA) · tumor vs normal (RNA) · all ABCA4 data types