Across TCGA cell cohorts, ABCA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,620 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ABCA4-associated GO terms across cancer lineages are Plasma membrane organization, Response to unfolded protein, and Negative regulation of RNA catabolic process. Each is linked with ABCA4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ABCA4-to-partner and partner-to-ABCA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA4→partner) and Y-score (partner→ABCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Plasma membrane organization →	+0.178	+0.460	<.001	.008	3	8
STOMACH	Response to unfolded protein →	+0.109	+0.556	<.001	.001	3	7
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.056	+0.626	<.001	.003	3	7
OESOPHAGUS	Negative regulation of mRNA catabolic process →	+0.067	+0.715	.003	.008	2	8
OESOPHAGUS	Negative regulation of mRNA metabolic process →	+0.064	+0.666	.005	.001	3	7
LARGE_INTESTINE	Pallium development →	+0.060	+0.365	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,620 associations by consensus.

Exploration

ABCA4 survival (RNA) · tumor vs normal (RNA) · all ABCA4 data types