ABCA13

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ABCA13 mass-spec protein differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ABCA13’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ABCA13 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types ABCA13 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD are the cancer types where ABCA13 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABCA13 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADFemaleAll−2.385.0044view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

ABCA13–COAD

Tumor-vs-normal mass-spec protein box plot for ABCA13 in COAD.

Open the COAD breakdown →

Exploration