ABCA13

Across TCGA patient cohorts, ABCA13 mutation is significantly associated with the RNA expression of many other genes, with 9,510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCA13-associated genes across cancer lineages are PDCD11, SNRPD3, and COX15. Each is linked with ABCA13 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCA13-to-partner and partner-to-ABCA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD11 grouped by ABCA13-low versus ABCA13-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA13→partner) and Y-score (partner→ABCA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PDCD11 →	+0.384	+2.502	.004	.001	3	6
UCEC	SNRPD3 →	+0.218	+1.222	<.001	<.001	3	6
UCEC	COX15 →	+0.354	+1.072	<.001	<.001	3	5
STAD	NGLY1 →	+0.322	+2.677	<.001	<.001	3	5
STAD	SASS6 →	+0.488	+1.938	<.001	.001	3	5
UCEC	TDRD10 →	-0.292	-1.521	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,510 associations by consensus.

PDCD11 by ABCA13 expression — STAD

Explore this box plot interactively →