ABCA13

Across TCGA patient cohorts, ABCA13 mutation is significantly associated with the total protein of many other genes, with 105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCA13-associated genes across cancer lineages are ERK2, PKC-b-II_pS660, and 4E-BP1. Each is linked with ABCA13 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCA13-to-partner and partner-to-ABCA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by ABCA13-low versus ABCA13-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA13→partner) and Y-score (partner→ABCA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ERK2 →	+0.200	+1.690	.039	.012	3	6
COAD	PKC-b-II_pS660 →	-0.315	-1.938	<.001	.001	3	5
HNSC	4E-BP1 →	+0.473	+3.459	.005	.005	2	6
COAD	eIF4E →	+0.185	+1.728	<.001	.001	3	4
STAD	MYH11 →	-1.360	-2.321	.003	.004	3	4
STAD	PCNA →	+0.277	+2.000	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

ERK2 by ABCA13 expression — LUAD

Explore this box plot interactively →