ABCA13

Across TCGA cell cohorts, ABCA13 mutation is significantly associated with the RNA expression of many other genes, with 2,345 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCA13-associated genes across cancer lineages are HSD17B6, REEP6, and ZNF18. Each is linked with ABCA13 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCA13-to-partner and partner-to-ABCA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSD17B6 grouped by ABCA13-low versus ABCA13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA13→partner) and Y-score (partner→ABCA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HSD17B6 →	+0.679	+3.228	.001	.004	3	4
CNS	REEP6 →	+0.630	+3.807	.001	<.001	3	4
LARGE_INTESTINE	ZNF18 →	+0.515	+1.894	<.001	<.001	3	4
CNS	LRRC73 →	+0.318	+2.910	.002	<.001	3	4
LARGE_INTESTINE	SGSM2 →	+0.852	+2.115	<.001	.001	3	4
BREAST	PRSS23 →	-2.205	-2.756	<.001	<.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

HSD17B6 by ABCA13 expression — BLOOD_Leukemia

Explore this box plot interactively →