ABCA1

Across TCGA patient cohorts, ABCA1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,894 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCA1-associated genes across cancer lineages are CCL18, ELK3, and PLAUR. Each is linked with ABCA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCA1-to-partner and partner-to-ABCA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCA1 versus CCL18 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA1→partner) and Y-score (partner→ABCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL18 →	+1.555	+0.342	.006	.003	3	5
COAD	ELK3 →	+0.898	+1.206	.003	.002	3	4
LUAD	PLAUR →	+0.947	+0.352	<.001	<.001	3	4
GBM	SLC11A1 →	+1.200	+0.500	<.001	<.001	3	4
COAD	THBS1 →	+1.624	+1.064	.002	.002	3	4
COAD	PARP15 →	+0.900	+0.823	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,894 associations by consensus.

ABCA1 vs CCL18 — UCEC

Explore this scatter interactively →