AARSD1P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AARSD1P1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. COAD shows the largest number of these associations.

The most reproducible AARSD1P1-associated genes across cancer lineages are SDR42E1P4, LONRF2P4, and PPP1R26P2. Each is linked with AARSD1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AARSD1P1-to-partner and partner-to-AARSD1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SDR42E1P4 grouped by AARSD1P1-low versus AARSD1P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AARSD1P1→partner) and Y-score (partner→AARSD1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSDR42E1P4 →+0.199+8.066<.001.00731
COADLONRF2P4 →+0.089+7.741<.001.00931
COADPPP1R26P2 →+0.014+7.741<.001.00931
COADMIR6868 →+0.567+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SDR42E1P4 by AARSD1P1 expression — UCEC

Box plot of SDR42E1P4 in AARSD1P1-low vs AARSD1P1-high samples in UCEC.

Explore this box plot interactively →

Exploration