AARSD1P1

Across TCGA pan-cancer cohorts, AARSD1P1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated AARSD1P1 data layer compared with 1 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher AARSD1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AARSD1P1 expression acts as an unfavorable survival marker, although some lineages such as LAML and BLCA show a favorable association.

UVM, KIRC, and LUAD are the cancer types where AARSD1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.326	0.857	.001	105	view →
KIRC	DFS	Tertile	All	0.513	0.709	.002	49	view →
LUAD	DFS	Tertile	IV	0.270	0.688	.008	42	view →
LAML	DFS	Tertile	All	0.646	0.302	.004	34	view →
SARC	OS	Tertile	All	0.646	0.869	.001	15	view →
BLCA	OS	Median	All	0.780	0.661	.003	13	view →
SKCM	OS	Quartile	II,III,IV	0.498	0.300	.012	12	view →
COAD	DFS	Quartile	II,III,IV	0.403	0.725	.001	12	view →
THCA	DFS	Quartile	II,III,IV	0.744	0.975	.002	11	view →
MESO	DFS	Quartile	IV	0.194	0.623	.020	10	view →
KICH	DFS	Tertile	III,IV	0.527	1.000	.036	8	view →
PCPG	DFS	Tertile	All	0.871	1.000	.004	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

AARSD1P1–UVM (DFS)

Open the UVM breakdown →