AARS2

Across TCGA patient cohorts, AARS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,610 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AARS2-associated proteins across cancer lineages are XPO5, PRCC, and RCC2. Each is linked with AARS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AARS2-to-partner and partner-to-AARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AARS2 versus XPO5 in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AARS2→partner) and Y-score (partner→AARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO5 →	+0.710	+0.639	<.001	<.001	3	7
GBM	PRCC →	+0.344	+0.344	<.001	<.001	3	6
GBM	RCC2 →	+0.452	+0.423	.001	<.001	3	6
LSCC	POLD1 →	+0.455	+0.528	<.001	<.001	3	6
LSCC	ZNF318 →	+0.451	+0.567	<.001	<.001	3	6
LSCC	MCM3 →	+0.842	+0.652	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,610 associations by consensus.

AARS2 vs XPO5 — LSCC

Explore this scatter interactively →