AARS1

Across TCGA patient cohorts, AARS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AARS1-associated proteins across cancer lineages are PSME3IP1, AP1G1, and CFDP1. Each is linked with AARS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AARS1-to-partner and partner-to-AARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AARS1 versus PSME3IP1 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AARS1→partner) and Y-score (partner→AARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSME3IP1 →	+0.301	+0.347	.002	<.001	3	7
UCEC	AP1G1 →	+0.258	+0.555	<.001	.005	3	7
OV	CFDP1 →	+0.419	+0.581	.002	.006	3	7
BRCA	WWP2 →	+0.350	+0.571	<.001	<.001	3	7
BRCA	EDC4 →	+0.290	+0.724	<.001	<.001	3	7
HNSC	ASNS →	+0.722	+0.575	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,470 associations by consensus.

AARS1 vs PSME3IP1 — GBM

Explore this scatter interactively →