Across TCGA patient cohorts, AARD RNA expression is significantly associated with the protein abundance of many other proteins, with 12,003 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AARD-associated proteins across cancer lineages are PTBP2, RPS8_T130, and PRKG1. Each is linked with AARD in more than 3 cancer types. Because this analysis shows association rather than direction, both AARD-to-partner and partner-to-AARD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AARD→partner) and Y-score (partner→AARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTBP2 →	+0.881	+0.498	<.001	<.001	3	4
UCEC	RPS8_T130 →	-0.697	-0.504	<.001	.001	3	4
COAD	PRKG1 →	+0.457	+0.343	<.001	<.001	3	4
PDAC	MYH10 →	+0.546	+0.248	<.001	<.001	3	4
COAD	SARM1 →	+0.301	+0.204	.001	.001	3	4
LSCC	SH2D3A_S180 →	-0.745	-0.784	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,003 associations by consensus.

Exploration

AARD survival (RNA) · tumor vs normal (RNA) · all AARD data types