Across TCGA patient cohorts, AARD protein abundance is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AARD-associated genes across cancer lineages are STX1A, SAMD10, and SMIM2. Each is linked with AARD in more than 1 cancer types. Because this analysis shows association rather than direction, both AARD-to-partner and partner-to-AARD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AARD→partner) and Y-score (partner→AARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STX1A →	-1.144	-0.703	.007	.001	3	1
BRCA	SAMD10 →	-0.808	-0.828	<.001	.008	3	1
BRCA	SMIM2 →	-0.138	-0.664	.002	.005	3	1
BRCA	CALHM4 →	-0.107	-0.804	<.001	.001	3	1
BRCA	PLIN4 →	+1.983	+0.656	.002	.004	3	1
BRCA	OR2B11 →	+0.080	+0.741	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

AARD survival (RNA) · tumor vs normal (RNA) · all AARD data types